Nilmaypharmablog

  What is 70%Isopropyl alcohol?  70ml ipa and 30 ml purified water and          make volume 100 ml that is 70% isopropyl alcohol.  [A].  WHy 70% Isopropyl alcohol is use in pharmaceutical industries as a disinfectant ? Whya 91% is not used?  70%Ipa  is common and most widely using disinfectant in the pharmaceutical industries, hospitals and other health care facilities. 70%ipa  is used for disinfection of hands and equipment surface and surgical devices. 70%Ipa  is only  acts as a disinfectant killing all surface microorganisms.  70   %Ipa  is  kills microorganisms by dissolving the plasma membrane of the cell wall. Plasma membrane of gram negative bacteria consist of thin layer of peptidoglycon that easily destroyed by the  ipa.  Water plays key important role which used to denature the proteins of cell membrane and acts as a catalyst in the reaction. Contact time of the  Ipa  with the organism also play an important role.  70% ipa  takes more time in evaporation from the surface, inc

  OBJECTIVE : To establish the procedure for monitoring the Personnel from the Production area for their personal hygiene practices. SCOPE: Personnel from the production  areas are monitored RESPONSIBILITY: Microbiologist  Quality Control To perform Personnel monitoring as per SOP. Head/Designee Production To provide the necessary support to carry out the activity. Head/Designee Quality Control To ensure that SOP is followed as written Head/Designee Quality Assurance  To ensure data compilation and review. ACCOUNTABILITY: Head/Designee Quality Control  Head/Designee Quality Assurance PROCEDURE : Personnel from the Production area are monitored to ensure that personnel hygiene practices are followed.  Preparation of Contact Plates The microbiologist prepares the plates by aseptically dispensing about 20 ml each of sterile melted MSA and MAC into sterile, empty contact plates of 50cm² area. After the agar solidifies, the plates are inverted and incubated at ambient temperature for 24 hrs